Nassar, Taher

Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug. [electronic resource] - Journal of controlled release : official journal of the Controlled Release Society Jan 2009 - 77-84 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-4995

10.1016/j.jconrel.2008.08.021 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism
Administration, Oral
Analysis of Variance
Animals
Area Under Curve
Biological Availability
Drug Delivery Systems--methods
Enterocytes--metabolism
Hypromellose Derivatives
Immunosuppressive Agents--chemistry
Intestinal Absorption
Intestinal Mucosa--metabolism
Intestines--pathology
Methylcellulose--analogs & derivatives
Microscopy, Electron, Scanning
Microspheres
Nanocapsules--chemistry
Particle Size
Plant Oils--chemistry
Polymethacrylic Acids--chemistry
Rats
Rats, Sprague-Dawley
Surface Properties
Swine
Tacrolimus--chemistry