TY - GEN AU - Hammond,Olivia AU - Reynolds,James AU - Rubinstein,Leonard J AU - Sikkema,Daniel AU - Marchese,Rocio D TI - Complexities of clinical assay development and optimization prior to first-in-man immunization trials - a description of immunogenicity assay development for the testing of samples from a phase 1 Alzheimer's vaccine trial SN - 1532-4230 PY - 2009///0211 KW - Alzheimer Vaccines KW - immunology KW - Amyloid beta-Peptides KW - Animals KW - Clinical Trials as Topic KW - Enzyme-Linked Immunosorbent Assay KW - standards KW - Humans KW - Immunoglobulin G KW - blood KW - Peptide Fragments KW - Research Design N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/15321810802329518 ER -