Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease. [electronic resource]
- Human molecular genetics Dec 2008
- 4001-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2083
10.1093/hmg/ddn303 doi
Cell Line Cell Line, Tumor DNA, Mitochondrial--drug effects Doxycycline--pharmacology Electron Transport--drug effects Electron Transport Complex I--biosynthesis Electron Transport Complex III--biosynthesis Electron Transport Complex IV--biosynthesis Enzyme Stability--drug effects Humans Kinetics Mitochondria--drug effects Models, Genetic Molecular Sequence Data NADH Dehydrogenase--genetics Optic Atrophy, Hereditary, Leber--genetics Oxidative Phosphorylation--drug effects Protein Subunits--genetics Sequence Analysis, DNA