TY - GEN AU - Pingali,Harikishore AU - Jain,Mukul AU - Shah,Shailesh AU - Basu,Sujay AU - Makadia,Pankaj AU - Goswami,Amitgiri AU - Zaware,Pandurang AU - Patil,Pravin AU - Godha,Atul AU - Giri,Suresh AU - Goel,Ashish AU - Patel,Megha AU - Patel,Harilal AU - Patel,Pankaj TI - Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent SN - 1464-3405 PY - 2009///0424 KW - Animals KW - Carboxylic Acids KW - chemical synthesis KW - Diabetes Mellitus, Type 2 KW - drug therapy KW - Dioxanes KW - Humans KW - Hypoglycemic Agents KW - Hypolipidemic Agents KW - Lipids KW - chemistry KW - Mesylates KW - Mice KW - Models, Chemical KW - PPAR alpha KW - metabolism KW - PPAR gamma KW - Peroxisome Proliferator-Activated Receptors KW - agonists KW - Rats KW - Rats, Wistar KW - Transcriptional Activation N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2008.08.112 ER -