Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production. [electronic resource]
- Toxicological sciences : an official journal of the Society of Toxicology Dec 2008
- 364-75 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0929
10.1093/toxsci/kfn195 doi
Base Sequence Cell Line, Tumor Cell Movement--drug effects Culture Media DNA Primers Gases Humans Lung Neoplasms--enzymology Matrix Metalloproteinase 2--biosynthesis NF-kappa B--metabolism Neoplasm Invasiveness Neoplasm Metastasis Nitric Oxide Synthase Type II--metabolism Nitrogen Oxides--pharmacology Proto-Oncogene Proteins c-jun--metabolism Reverse Transcriptase Polymerase Chain Reaction