TY - GEN AU - Liu,Y AU - Borchert,G L AU - Surazynski,A AU - Phang,J M TI - Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers SN - 1476-5594 PY - 2008///1210 KW - Apoptosis KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - enzymology KW - Cyclooxygenase 2 KW - genetics KW - Dinoprostone KW - metabolism KW - Down-Regulation KW - ErbB Receptors KW - Gene Expression Regulation, Neoplastic KW - Glycogen Synthase Kinase 3 KW - Glycogen Synthase Kinase 3 beta KW - Humans KW - Mitochondrial Proteins KW - biosynthesis KW - Phosphorylation KW - Proline KW - Proline Oxidase KW - Reactive Oxygen Species KW - Signal Transduction KW - Transcription, Genetic KW - Tumor Suppressor Protein p53 KW - Wnt Proteins KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1038/onc.2008.322 ER -