TY  - GEN
AU  - Trani,Giancarlo
AU  - Baddeley,Stuart M
AU  - Briggs,Michael A
AU  - Chuang,Tsu T
AU  - Deeks,Nigel J
AU  - Johnson,Christopher N
AU  - Khazragi,Abir A
AU  - Mead,Tania L
AU  - Medhurst,Andrew D
AU  - Milner,Peter H
AU  - Quinn,Leann P
AU  - Ray,Alison M
AU  - Rivers,Dean A
AU  - Stean,Tania O
AU  - Stemp,Geoffrey
AU  - Trail,Brenda K
AU  - Witty,David R
TI  - Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists
SN  - 1464-3405
PY  - 2009///0424
KW  - Animals
KW  - Antidepressive Agents, Tricyclic
KW  - chemical synthesis
KW  - Blood-Brain Barrier
KW  - drug effects
KW  - Brain
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - chemistry
KW  - Humans
KW  - Hydrogen Bonding
KW  - Microsomes
KW  - Models, Chemical
KW  - Molecular Conformation
KW  - Protein Isoforms
KW  - Rats
KW  - Receptors, Serotonin
KW  - Serotonin Antagonists
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2008.08.010
ER  -