Trani, Giancarlo <br/><br/>
Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Oct 2008 
 - 5698-700 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2008.08.010  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antidepressive Agents, Tricyclic--chemical synthesis<br/>Blood-Brain Barrier--drug effects<br/>Brain--drug effects<br/>Chemistry, Pharmaceutical--methods<br/>Cytochrome P-450 CYP3A<br/>Cytochrome P-450 Enzyme System--chemistry<br/>Humans<br/>Hydrogen Bonding<br/>Microsomes--drug effects<br/>Models, Chemical<br/>Molecular Conformation<br/>Protein Isoforms<br/>Rats<br/>Receptors, Serotonin--chemistry<br/>Serotonin Antagonists--chemical synthesis