Ghosh, Arun K <br/><br/>
Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies.  [electronic resource] 

 -  Journal of medicinal chemistry  Oct 2008 
 - 6021-33 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm8004543  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antiviral Agents--chemical synthesis<br/>Cell Survival--drug effects<br/>Crystallography, X-Ray<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Ethers, Cyclic--chemical synthesis<br/>HIV Protease--chemistry<br/>HIV Protease Inhibitors--chemical synthesis<br/>HIV-1--drug effects<br/>Humans<br/>Hydrogen Bonding<br/>Ligands<br/>Microbial Sensitivity Tests<br/>Models, Molecular<br/>Molecular Structure<br/>Polyesters--chemical synthesis<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>T-Lymphocytes--drug effects<br/>Water--chemistry