TY  - GEN
AU  - Powers,Marissa V
AU  - Clarke,Paul A
AU  - Workman,Paul
TI  - Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis
SN  - 1878-3686
PY  - 2008///1015
KW  - Apoptosis
KW  - drug effects
KW  - Benzoquinones
KW  - pharmacology
KW  - Boronic Acids
KW  - Bortezomib
KW  - Cell Cycle
KW  - Cell Line
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cyclin-Dependent Kinase 4
KW  - metabolism
KW  - HCT116 Cells
KW  - HSC70 Heat-Shock Proteins
KW  - genetics
KW  - HSP70 Heat-Shock Proteins
KW  - HSP72 Heat-Shock Proteins
KW  - HSP90 Heat-Shock Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Kinetics
KW  - Lactams, Macrocyclic
KW  - Neoplasms
KW  - Poly(ADP-ribose) Polymerases
KW  - Protease Inhibitors
KW  - Proteasome Endopeptidase Complex
KW  - Proteasome Inhibitors
KW  - Protein Isoforms
KW  - Proto-Oncogene Proteins c-raf
KW  - Pyrazines
KW  - RNA, Small Interfering
KW  - Transfection
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ccr.2008.08.002
ER  -