Powers, Marissa V <br/><br/>
Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.  [electronic resource] 

 -  Cancer cell  Sep 2008 
 - 250-62 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1878-3686 
<br/><br/><label>Standard No.: </label>10.1016/j.ccr.2008.08.002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Benzoquinones--pharmacology<br/>Boronic Acids--pharmacology<br/>Bortezomib<br/>Cell Cycle--drug effects<br/>Cell Line<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase 4--metabolism<br/>HCT116 Cells<br/>HSC70 Heat-Shock Proteins--genetics<br/>HSP70 Heat-Shock Proteins--metabolism<br/>HSP72 Heat-Shock Proteins--genetics<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Humans<br/>Kinetics<br/>Lactams, Macrocyclic--pharmacology<br/>Neoplasms--genetics<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Protease Inhibitors--pharmacology<br/>Proteasome Endopeptidase Complex--metabolism<br/>Proteasome Inhibitors<br/>Protein Isoforms--genetics<br/>Proto-Oncogene Proteins c-raf--metabolism<br/>Pyrazines--pharmacology<br/>RNA, Small Interfering--genetics<br/>Transfection<br/>Ubiquitination