TY  - GEN
AU  - Tian,Xinrong
AU  - Switzer,Adrian G
AU  - Derose,Steve A
AU  - Mishra,Rajesh K
AU  - Solinsky,Mark G
AU  - Mumin,Rashid N
AU  - Ebetino,Frank H
AU  - Jayasinghe,Lalith R
AU  - Webster,Mark E
AU  - Colson,Anny-Odile
AU  - Crossdoersen,Doreen
AU  - Pinney,Beth B
AU  - Farmer,Julie A
AU  - Dowty,Martin E
AU  - Obringer,Cindy M
AU  - Cruze,Charles A
AU  - Burklow,Melissa L
AU  - Suchanek,Paula M
AU  - Dong,Lily
AU  - Dirr,Mary Kay
AU  - Sheldon,Russell J
AU  - Wos,John A
TI  - Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents
SN  - 1520-4804
PY  - 2008///1030
KW  - Administration, Oral
KW  - Animals
KW  - Anti-Obesity Agents
KW  - chemistry
KW  - Biological Availability
KW  - Diet
KW  - Disease Models, Animal
KW  - Dogs
KW  - Drug Design
KW  - Drug Evaluation, Preclinical
KW  - Eating
KW  - drug effects
KW  - Male
KW  - Molecular Conformation
KW  - Obesity
KW  - drug therapy
KW  - Piperazines
KW  - Rats
KW  - Receptor, Melanocortin, Type 4
KW  - agonists
KW  - Stereoisomerism
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm800525p
ER  -