Grogan, Shawn P

Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site. [electronic resource] - Arthritis and rheumatism Sep 2008 - 2754-63 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1529-0131

10.1002/art.23730 doi


Basic Helix-Loop-Helix Transcription Factors--genetics
Blotting, Western
Bone Morphogenetic Protein 6--pharmacology
Carbamates--pharmacology
Cell Cycle Proteins--genetics
Cell Differentiation--physiology
Cells, Cultured
Chondrogenesis--drug effects
Chromatin Immunoprecipitation
Collagen Type II--metabolism
Dipeptides--pharmacology
Fibroblast Growth Factor 2--pharmacology
Homeodomain Proteins--genetics
Humans
Mesenchymal Stem Cells
Receptors, Notch--genetics
Regulatory Sequences, Nucleic Acid--genetics
Repressor Proteins--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Time Factors
Transcription Factor HES-1
Transforming Growth Factor beta3--pharmacology