Shibata, Tatsuhiro <br/><br/>
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Sep 2008 
 - 13568-73 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.0806268105  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Active Transport, Cell Nucleus<br/>Antineoplastic Agents--pharmacology<br/>Base Sequence<br/>Cell Line, Tumor<br/>Cullin Proteins--metabolism<br/>Down-Regulation--drug effects<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Intracellular Signaling Peptides and Proteins--metabolism<br/>Kelch-Like ECH-Associated Protein 1<br/>Models, Molecular<br/>Mutation--genetics<br/>NF-E2-Related Factor 2--chemistry<br/>Neoplasms--genetics<br/>Oxidative Stress<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Substrate Specificity<br/>Transcription, Genetic--genetics