Larivière, Sigolène

Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3',5'-cyclic adenosine-5'-monophosphate pathway in LbetaT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor. [electronic resource] - Endocrinology Dec 2008 - 6389-98 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0013-7227

10.1210/en.2008-0504 doi


Animals
Blotting, Western
Calcium--metabolism
Cell Line
Cyclic AMP--metabolism
Gonadotrophs--cytology
Gonadotropin-Releasing Hormone--agonists
Mice
Phosphorylation--drug effects
Pituitary Adenylate Cyclase-Activating Polypeptide--genetics
Protein Binding--drug effects
Protein Isoforms--genetics
Protein Kinase C--metabolism
Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide--genetics
Reverse Transcriptase Polymerase Chain Reaction
Triptorelin Pamoate--pharmacology