Frohn, Mike <br/><br/>
Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Sep 2008 
 - 5023-6 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2008.08.012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aza Compounds--chemical synthesis<br/>Basic Helix-Loop-Helix Transcription Factors<br/>Benzimidazoles--chemical synthesis<br/>Combinatorial Chemistry Techniques<br/>Crystallography, X-Ray<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors<br/>Hypoxia-Inducible Factor-Proline Dioxygenases<br/>Models, Molecular<br/>Molecular Structure<br/>Procollagen-Proline Dioxygenase--antagonists & inhibitors<br/>Structure-Activity Relationship