Blier, P Resiliency of monoaminergic systems: the 80% rule and its relevance to drug development. [electronic resource] - Journal of psychopharmacology (Oxford, England) Aug 2008 - 587-9 p. digital Publication Type: Editorial ISSN: 0269-8811 Standard No.: 10.1177/0269881108095680 doi Subjects--Topical Terms: AnimalsAntidepressive Agents--therapeutic useBiogenic Amines--physiologyBiogenic Monoamines--physiologyBrain--drug effectsDopamine--physiologyHumansMonoamine Oxidase Inhibitors--therapeutic useNorepinephrine--physiologyParkinson Disease--drug therapySerotonin--physiology