TY - GEN AU - Rasko,David A AU - Moreira,Cristiano G AU - Li,De Run AU - Reading,Nicola C AU - Ritchie,Jennifer M AU - Waldor,Matthew K AU - Williams,Noelle AU - Taussig,Ron AU - Wei,Shuguang AU - Roth,Michael AU - Hughes,David T AU - Huntley,Jason F AU - Fina,Maggy W AU - Falck,John R AU - Sperandio,Vanessa TI - Targeting QseC signaling and virulence for antibiotic development SN - 1095-9203 PY - 2008///0903 KW - Animals KW - Anti-Bacterial Agents KW - administration & dosage KW - Enterohemorrhagic Escherichia coli KW - drug effects KW - Escherichia coli Infections KW - drug therapy KW - Escherichia coli Proteins KW - antagonists & inhibitors KW - Francisella tularensis KW - Gene Expression Regulation, Bacterial KW - Gram-Negative Bacterial Infections KW - Histidine Kinase KW - Mice KW - Norepinephrine KW - metabolism KW - Phosphorylation KW - Protein Kinases KW - genetics KW - Rabbits KW - Salmonella Infections, Animal KW - Salmonella typhimurium KW - Signal Transduction KW - Small Molecule Libraries KW - Sulfonamides KW - Tularemia KW - Virulence Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1160354 ER -