TY - GEN AU - Lu,Xiaoqing AU - Malumbres,Raquel AU - Shields,Benjamin AU - Jiang,Xiaoyu AU - Sarosiek,Kristopher A AU - Natkunam,Yasodha AU - Tiganis,Tony AU - Lossos,Izidore S TI - PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling SN - 1528-0020 PY - 2008///1125 KW - Animals KW - Enzyme Inhibitors KW - pharmacology KW - Gene Expression Regulation, Enzymologic KW - drug effects KW - HeLa Cells KW - Humans KW - Inflammation KW - genetics KW - Interleukin-4 KW - metabolism KW - Lymphoma, Large B-Cell, Diffuse KW - Mice KW - Mice, Knockout KW - Mutation, Missense KW - Phosphatidylinositol 3-Kinases KW - Phosphorylation KW - Protein Tyrosine Phosphatase, Non-Receptor Type 1 KW - biosynthesis KW - RNA, Messenger KW - STAT5 Transcription Factor KW - STAT6 Transcription Factor KW - Signal Transduction KW - physiology KW - Staurosporine KW - TYK2 Kinase KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2008-03-148726 ER -