Lu, Xiaoqing
PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. [electronic resource]
- Blood Nov 2008
- 4098-108 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2008-03-148726 doi
Animals
Enzyme Inhibitors--pharmacology
Gene Expression Regulation, Enzymologic--drug effects
HeLa Cells
Humans
Inflammation--genetics
Interleukin-4--metabolism
Lymphoma, Large B-Cell, Diffuse--genetics
Mice
Mice, Knockout
Mutation, Missense
Phosphatidylinositol 3-Kinases--genetics
Phosphorylation--drug effects
Protein Tyrosine Phosphatase, Non-Receptor Type 1--biosynthesis
RNA, Messenger--biosynthesis
STAT5 Transcription Factor--genetics
STAT6 Transcription Factor--genetics
Signal Transduction--physiology
Staurosporine--pharmacology
TYK2 Kinase--genetics
Tumor Suppressor Proteins--genetics