TY - GEN AU - Richardson,Robyn D AU - Ma,Gil AU - Oyola,Yatsandra AU - Zancanella,Manuel AU - Knowles,Lynn M AU - Cieplak,Piotr AU - Romo,Daniel AU - Smith,Jeffrey W TI - Synthesis of novel beta-lactone inhibitors of fatty acid synthase SN - 1520-4804 PY - 2008///1024 KW - Antineoplastic Agents KW - chemical synthesis KW - Cell Death KW - drug effects KW - Cell Line, Tumor KW - Fatty Acid Synthases KW - antagonists & inhibitors KW - Fibroblasts KW - Humans KW - Lactones KW - Neoplasms KW - drug therapy KW - Orlistat KW - Solubility KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/jm800321h ER -