Richardson, Robyn D <br/><br/>
Synthesis of novel beta-lactone inhibitors of fatty acid synthase.  [electronic resource] 

 -  Journal of medicinal chemistry  Sep 2008 
 - 5285-96 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm800321h  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Cell Death--drug effects<br/>Cell Line, Tumor<br/>Fatty Acid Synthases--antagonists & inhibitors<br/>Fibroblasts<br/>Humans<br/>Lactones--chemical synthesis<br/>Neoplasms--drug therapy<br/>Orlistat<br/>Solubility<br/>Structure-Activity Relationship