Krige, David <br/><br/>
CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells.  [electronic resource] 

 -  Cancer research  Aug 2008 
 - 6669-79 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-07-6627  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acids--metabolism<br/>Aminopeptidases--antagonists & inhibitors<br/>Animals<br/>Biomarkers, Tumor--metabolism<br/>Cell Proliferation--drug effects<br/>Electrophoresis, Polyacrylamide Gel<br/>Enzyme Inhibitors--pharmacology<br/>Eukaryotic Initiation Factor-2--metabolism<br/>Gene Expression Profiling<br/>Gene Expression Regulation, Leukemic<br/>Glycine--analogs & derivatives<br/>HL-60 Cells--drug effects<br/>Humans<br/>Hydroxamic Acids--pharmacology<br/>Immunoblotting<br/>Leucine--analogs & derivatives<br/>Mice<br/>Oligonucleotide Array Sequence Analysis<br/>Peptide Fragments--metabolism<br/>Phenylalanine--analogs & derivatives<br/>Phosphorylation--drug effects<br/>Protein Kinases--metabolism<br/>Protein Synthesis Inhibitors<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>RNA, Messenger--genetics<br/>Rats<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>TOR Serine-Threonine Kinases<br/>Thiophenes--pharmacology<br/>Tumor Cells, Cultured<br/>Xenograft Model Antitumor Assays