TY  - GEN
AU  - Abdel-Hafez,Atef A
AU  - Abdel-Wahab,Basel A
TI  - 5-(4-Chlorophenyl)-5,6-dihydro-1,3-oxazepin-7(4H)-one derivatives as lipophilic cyclic analogues of baclofen: design, synthesis, and neuropharmacological evaluation
SN  - 1464-3391
PY  - 2008///1103
KW  - Animals
KW  - Baclofen
KW  - chemistry
KW  - Cognition Disorders
KW  - drug therapy
KW  - Cyclization
KW  - Dose-Response Relationship, Drug
KW  - Drug Design
KW  - Drug Evaluation, Preclinical
KW  - GABA Agonists
KW  - chemical synthesis
KW  - GABA-B Receptor Agonists
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Injections, Intraperitoneal
KW  - Magnetic Resonance Spectroscopy
KW  - methods
KW  - Male
KW  - Mice
KW  - Molecular Structure
KW  - Motor Activity
KW  - drug effects
KW  - Muscle Relaxation
KW  - Oxazepines
KW  - Pain
KW  - Receptors, GABA-B
KW  - Reference Standards
KW  - Stereoisomerism
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmc.2008.07.064
ER  -