Abdel-Hafez, Atef A <br/><br/>
5-(4-Chlorophenyl)-5,6-dihydro-1,3-oxazepin-7(4H)-one derivatives as lipophilic cyclic analogues of baclofen: design, synthesis, and neuropharmacological evaluation.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Sep 2008 
 - 7983-91 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2008.07.064  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Baclofen--chemistry<br/>Cognition Disorders--drug therapy<br/>Cyclization<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>GABA Agonists--chemical synthesis<br/>GABA-B Receptor Agonists<br/>Hydrophobic and Hydrophilic Interactions<br/>Injections, Intraperitoneal<br/>Magnetic Resonance Spectroscopy--methods<br/>Male<br/>Mice<br/>Molecular Structure<br/>Motor Activity--drug effects<br/>Muscle Relaxation--drug effects<br/>Oxazepines--chemical synthesis<br/>Pain--drug therapy<br/>Receptors, GABA-B--chemistry<br/>Reference Standards<br/>Stereoisomerism