TY - GEN AU - McCubrey,J A AU - Abrams,S L AU - Ligresti,G AU - Misaghian,N AU - Wong,E W T AU - Steelman,L S AU - Bäsecke,J AU - Troppmair,J AU - Libra,M AU - Nicoletti,F AU - Molton,S AU - McMahon,M AU - Evangelisti,C AU - Martelli,A M TI - Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance SN - 1476-5551 PY - 2008///1211 KW - Animals KW - Annexin A5 KW - metabolism KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Caspases KW - Cells, Cultured KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - Doxorubicin KW - Drug Resistance KW - Enzyme Activation KW - Enzyme Inhibitors KW - Extracellular Signal-Regulated MAP Kinases KW - antagonists & inhibitors KW - Genes, Dominant KW - Hematopoietic Stem Cells KW - Imidazoles KW - Leupeptins KW - Mice KW - Mitogen-Activated Protein Kinase Kinases KW - Phosphorylation KW - Piperazines KW - Proto-Oncogene Proteins c-mdm2 KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Tumor Suppressor Protein p53 KW - raf Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2008.207 ER -