TY - GEN AU - Zhuang,D AU - Mannava,S AU - Grachtchouk,V AU - Tang,W-H AU - Patil,S AU - Wawrzyniak,J A AU - Berman,A E AU - Giordano,T J AU - Prochownik,E V AU - Soengas,M S AU - Nikiforov,M A TI - C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells SN - 1476-5594 PY - 2008///1118 KW - Cell Line, Tumor KW - Cellular Senescence KW - drug effects KW - Cyclin-Dependent Kinase Inhibitor p16 KW - genetics KW - Disease Progression KW - Gene Deletion KW - Gene Expression KW - Humans KW - Melanocytes KW - metabolism KW - Melanoma KW - enzymology KW - Mitogen-Activated Protein Kinase Kinases KW - antagonists & inhibitors KW - Neoplasm Metastasis KW - Phenotype KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Protein Kinase Inhibitors KW - pharmacology KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-myc KW - Tumor Suppressor Protein p53 KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2008.258 ER -