Musilek, Kamil <br/><br/>
Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Sep 2008 
 - 8218-23 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2008.07.036  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholinesterase--chemistry<br/>Animals<br/>Brain--enzymology<br/>Cholinesterase Inhibitors--pharmacology<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>Enzyme Activation--drug effects<br/>Enzyme Activators--chemical synthesis<br/>Models, Biological<br/>Molecular Structure<br/>Organophosphates--antagonists & inhibitors<br/>Paraoxon--antagonists & inhibitors<br/>Pyridinium Compounds--chemical synthesis<br/>Rats<br/>Stereoisomerism<br/>Structure-Activity Relationship