Pinto-Bazurco Mendieta, Mariano A E

Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer. [electronic resource] - Journal of medicinal chemistry Aug 2008 - 5009-18 p. digital

Publication Type: Journal Article

1520-4804

10.1021/jm800355c doi


Androstenes
Androstenols--chemical synthesis
Biphenyl Compounds--chemical synthesis
Enzyme Inhibitors--chemical synthesis
Humans
Male
Models, Molecular
Prostatic Neoplasms--drug therapy
Recombinant Proteins--drug effects
Steroid 17-alpha-Hydroxylase--antagonists & inhibitors