TY - GEN AU - Azad,Nilofer S AU - Posadas,Edwin M AU - Kwitkowski,Virginia E AU - Steinberg,Seth M AU - Jain,Lokesh AU - Annunziata,Christina M AU - Minasian,Lori AU - Sarosy,Gisele AU - Kotz,Herbert L AU - Premkumar,Ahalya AU - Cao,Liang AU - McNally,Deborah AU - Chow,Catherine AU - Chen,Helen X AU - Wright,John J AU - Figg,William D AU - Kohn,Elise C TI - Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity SN - 1527-7755 PY - 2008///0814 KW - Administration, Oral KW - Adult KW - Aged KW - Angiogenesis Inhibitors KW - administration & dosage KW - Antibodies, Monoclonal KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Benzenesulfonates KW - Bevacizumab KW - Drug Administration Schedule KW - Female KW - Humans KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Neoplasm Staging KW - Neoplasms KW - drug therapy KW - Niacinamide KW - analogs & derivatives KW - Ovarian Neoplasms KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Pyridines KW - Receptors, Vascular Endothelial Growth Factor KW - antagonists & inhibitors KW - Sorafenib KW - Treatment Outcome KW - Vascular Endothelial Growth Factor A KW - raf Kinases N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1200/JCO.2007.10.8332 ER -