4-thio-deoxyuridylate-modified thrombin aptamer and its inhibitory effect on fibrin clot formation, platelet aggregation and thrombus growth on subendothelial matrix. [electronic resource]
- Journal of thrombosis and haemostasis : JTH Oct 2008
- 1764-71 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-7836
10.1111/j.1538-7836.2008.03106.x doi
Aptamers, Nucleotide--chemical synthesis Base Sequence Blood Coagulation--drug effects Deoxyuracil Nucleotides Drug Evaluation, Preclinical Endothelial Cells Endothelium, Vascular--cytology Fibrinopeptide A--metabolism Humans Perfusion Platelet Aggregation--drug effects Structure-Activity Relationship Thionucleotides Thrombosis--prevention & control