TY  - GEN
AU  - Dickson,Patricia
AU  - Peinovich,Maryn
AU  - McEntee,Michael
AU  - Lester,Thomas
AU  - Le,Steven
AU  - Krieger,Aimee
AU  - Manuel,Hayden
AU  - Jabagat,Catherine
AU  - Passage,Merry
AU  - Kakkis,Emil D
TI  - Immune tolerance improves the efficacy of enzyme replacement therapy in canine mucopolysaccharidosis I
SN  - 0021-9738
PY  - 2008///0925
KW  - Animals
KW  - Azathioprine
KW  - pharmacology
KW  - Cyclosporine
KW  - Disease Models, Animal
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Glycosaminoglycans
KW  - metabolism
KW  - Humans
KW  - Iduronidase
KW  - genetics
KW  - Immune Tolerance
KW  - Immunosuppressive Agents
KW  - Kidney
KW  - drug effects
KW  - Lysosomal Storage Diseases
KW  - drug therapy
KW  - Lysosomes
KW  - Mitral Valve
KW  - Mucopolysaccharidosis I
KW  - Recombinant Proteins
KW  - administration & dosage
KW  - Synovial Membrane
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI34676
ER  -