The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid. [electronic resource]
- Molecular endocrinology (Baltimore, Md.) Oct 2008
- 2260-7 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0888-8809
10.1210/me.2008-0148 doi
3T3-L1 Cells 5' Untranslated Regions AMP-Activated Protein Kinases Adipocytes--cytology Animals Humans Leptin--biosynthesis Mechanistic Target of Rapamycin Complex 1 Mice Mice, Knockout Monomeric GTP-Binding Proteins--genetics Multienzyme Complexes--genetics Multiprotein Complexes Neuropeptides--genetics Protein Biosynthesis Protein Serine-Threonine Kinases--genetics Proteins RNA, Messenger--genetics Ras Homolog Enriched in Brain Protein TOR Serine-Threonine Kinases Transcription Factors--genetics Tuberous Sclerosis Complex 2 Protein Tumor Suppressor Proteins--genetics