TY - GEN AU - Sridar,Chitra AU - Kent,Ute M AU - Noon,Kate AU - McCall,Alecia AU - Alworth,Bill AU - Foroozesh,Maryam AU - Hollenberg,Paul F TI - Differential inhibition of cytochromes P450 3A4 and 3A5 by the newly synthesized coumarin derivatives 7-coumarin propargyl ether and 7-(4-trifluoromethyl)coumarin propargyl ether SN - 1521-009X PY - 2009///1113 KW - Alkynes KW - chemical synthesis KW - Coumarins KW - Cytochrome P-450 CYP3A KW - metabolism KW - Cytochrome P-450 CYP3A Inhibitors KW - Enzyme Activation KW - drug effects KW - Enzyme Inhibitors KW - Ethers KW - Humans KW - Imidazoles KW - Microsomes, Liver N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1124/dmd.108.021493 ER -