Lanke, Elsa <br/><br/>
N1421K mutation in the glycoprotein Ib binding domain impairs ristocetin- and botrocetin-mediated binding of von Willebrand factor to platelets.  [electronic resource] 

 -  European journal of haematology  Nov 2008 
 - 384-90 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1600-0609 
<br/><br/><label>Standard No.: </label>10.1111/j.1600-0609.2008.01123.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Substitution<br/>Animals<br/>Anti-Bacterial Agents--pharmacology<br/>Binding Sites--genetics<br/>Blood Platelets--metabolism<br/>COS Cells<br/>Chlorocebus aethiops<br/>Collagen--metabolism<br/>Crotalid Venoms--pharmacology<br/>Factor VIII--genetics<br/>Family<br/>Female<br/>Heterozygote<br/>Humans<br/>Male<br/>Mutation, Missense<br/>Pedigree<br/>Platelet Adhesiveness--drug effects<br/>Platelet Aggregation--drug effects<br/>Platelet Glycoprotein GPIb-IX Complex--genetics<br/>Protein Binding--drug effects<br/>Protein Structure, Tertiary--genetics<br/>Ristocetin--pharmacology<br/>von Willebrand Diseases--genetics<br/>von Willebrand Factor--genetics