TY  - GEN
AU  - Wang,Shizhen Emily
AU  - Xiang,Bin
AU  - Guix,Marta
AU  - Olivares,Maria Graciela
AU  - Parker,Joel
AU  - Chung,Christine H
AU  - Pandiella,Atanasio
AU  - Arteaga,Carlos L
TI  - Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
SN  - 1098-5549
PY  - 2008///0929
KW  - ADAM Proteins
KW  - genetics
KW  - ADAM17 Protein
KW  - Antibodies, Monoclonal
KW  - therapeutic use
KW  - Antibodies, Monoclonal, Humanized
KW  - Antineoplastic Agents
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cells, Cultured
KW  - Enzyme Activation
KW  - Female
KW  - Gene Expression Profiling
KW  - Humans
KW  - Oligonucleotide Array Sequence Analysis
KW  - Phosphatidylinositol 3-Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA Interference
KW  - Receptor, ErbB-2
KW  - Signal Transduction
KW  - physiology
KW  - Transforming Growth Factor alpha
KW  - metabolism
KW  - Transforming Growth Factor beta
KW  - Trastuzumab
KW  - Treatment Outcome
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1128/MCB.00787-08
ER  -