RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. [electronic resource]
- Molecular cancer therapeutics Jul 2008
- 2160-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-7163
10.1158/1535-7163.MCT-08-0046 doi
Animals Antineoplastic Combined Chemotherapy Protocols--pharmacology Apoptosis--drug effects Bone Neoplasms--complications Cell Line, Tumor Cell Proliferation--drug effects Docetaxel Humans Male Mice Mice, Nude Osteolysis--complications Osteoprotegerin--pharmacology Prostatic Neoplasms--pathology RANK Ligand--antagonists & inhibitors Receptors, Fc Survival Analysis Taxoids--pharmacology Tumor Burden--drug effects Whole Body Imaging Xenograft Model Antitumor Assays