TY - GEN AU - Giovannetti,E AU - Backus,H H J AU - Wouters,D AU - Peters,G J TI - Functional inactivity and mutations of p53 differentially affect sensitivity to 5-fluorouracil and antifolate inhibitors of thymidylate synthase (TS) by altering TS levels in colorectal cancer cells SN - 1532-2335 PY - 2008///1030 KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - drug therapy KW - Fluorouracil KW - pharmacology KW - Folic Acid Antagonists KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Inhibitory Concentration 50 KW - Mutation KW - RNA, Messenger KW - genetics KW - Substrate Specificity KW - Thymidylate Synthase KW - antagonists & inhibitors KW - Transfection KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/15257770802145512 ER -