Mayr, Florian B
Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia. [electronic resource]
- Shock (Augusta, Ga.) Apr 2008
- 475-82 p. digital
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
ISSN: 1073-2322
Standard No.: 10.1097/shk.0b013e318142c4e8 doi
Subjects--Topical Terms: Adolescent Adult Blood Coagulation--drug effects Blood Platelets--drug effects Cell Adhesion Molecules--antagonists & inhibitors Cross-Over Studies Double-Blind Method Endotoxemia--chemically induced Flow Cytometry Hemodynamics--drug effects Hexanes--pharmacology Humans Inflammation--metabolism Interleukin-6--metabolism Leukocytes--drug effects Lipopolysaccharides Male Mannose--analogs & derivatives Platelet Membrane Glycoprotein IIb--metabolism RNA, Messenger--genetics Reverse Transcriptase Polymerase Chain Reaction Selectins--metabolism Thromboplastin--genetics Time Factors Tumor Necrosis Factor-alpha--metabolism