Mayr, Florian B

Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia. [electronic resource] - Shock (Augusta, Ga.) Apr 2008 - 475-82 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1073-2322

10.1097/shk.0b013e318142c4e8 doi


Adolescent
Adult
Blood Coagulation--drug effects
Blood Platelets--drug effects
Cell Adhesion Molecules--antagonists & inhibitors
Cross-Over Studies
Double-Blind Method
Endotoxemia--chemically induced
Flow Cytometry
Hemodynamics--drug effects
Hexanes--pharmacology
Humans
Inflammation--metabolism
Interleukin-6--metabolism
Leukocytes--drug effects
Lipopolysaccharides
Male
Mannose--analogs & derivatives
Platelet Membrane Glycoprotein IIb--metabolism
RNA, Messenger--genetics
Reverse Transcriptase Polymerase Chain Reaction
Selectins--metabolism
Thromboplastin--genetics
Time Factors
Tumor Necrosis Factor-alpha--metabolism