Hoffmann, Jens <br/><br/>
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone.  [electronic resource] 

 -  Cancer research  Jul 2008 
 - 5301-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-08-0237  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacokinetics<br/>Apoptosis--drug effects<br/>Benzothiazoles--pharmacokinetics<br/>Epothilones--pharmacokinetics<br/>HCT116 Cells<br/>HeLa Cells<br/>Humans<br/>Mice<br/>Mitochondria--drug effects<br/>Neoplasms--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--physiology<br/>Tissue Distribution<br/>Tubulin--drug effects<br/>Tumor Cells, Cultured<br/>Xenograft Model Antitumor Assays