Khawaja, N R <br/><br/>
Patupilone-induced apoptosis is mediated by mitochondrial reactive oxygen species through Bim relocalization to mitochondria.  [electronic resource] 

 -  Molecular pharmacology  Oct 2008 
 - 1072-83 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-0111 
<br/><br/><label>Standard No.: </label>10.1124/mol.108.048405  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Cytochromes c--metabolism<br/>Dose-Response Relationship, Drug<br/>Epothilones--pharmacology<br/>Humans<br/>Indicators and Reagents--metabolism<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mitochondria--metabolism<br/>Neuroblastoma--drug therapy<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction--physiology<br/>Tetrazolium Salts--metabolism<br/>Time Factors<br/>Tubulin Modulators--pharmacology<br/>bcl-2-Associated X Protein--metabolism