TY  - GEN
AU  - Alvarez,Alejandra R
AU  - Klein,Andrés
AU  - Castro,Juan
AU  - Cancino,Gonzalo I
AU  - Amigo,Julio
AU  - Mosqueira,Matías
AU  - Vargas,Lina M
AU  - Yévenes,L Fernanda
AU  - Bronfman,Francisca C
AU  - Zanlungo,Silvana
TI  - Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease
SN  - 1530-6860
PY  - 2008///1021
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Benzamides
KW  - Cell Survival
KW  - Cerebellar Cortex
KW  - DNA-Binding Proteins
KW  - metabolism
KW  - Disease Models, Animal
KW  - Gene Expression
KW  - Imatinib Mesylate
KW  - Intracellular Signaling Peptides and Proteins
KW  - Mice
KW  - Mice, Knockout
KW  - Motor Activity
KW  - Niemann-Pick C1 Protein
KW  - Niemann-Pick Disease, Type C
KW  - drug therapy
KW  - Nuclear Proteins
KW  - Piperazines
KW  - therapeutic use
KW  - Proteins
KW  - genetics
KW  - Proto-Oncogene Proteins c-abl
KW  - Purkinje Cells
KW  - Pyrimidines
KW  - RNA, Messenger
KW  - antagonists & inhibitors
KW  - Tumor Protein p73
KW  - Tumor Suppressor Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1096/fj.07-102715
ER  -