Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells. [electronic resource]
- Molecular cancer Jun 2008
- 60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1476-4598
10.1186/1476-4598-7-60 doi
Antineoplastic Agents--pharmacology Apoptosis--drug effects Breast Neoplasms--genetics Caspase 3--metabolism Cell Line, Tumor Collagen Type XI--metabolism Drug Resistance, Neoplasm--drug effects Enzyme Activation--drug effects Humans Intracellular Signaling Peptides and Proteins--genetics Mitochondrial Proteins--genetics Photosensitizing Agents--pharmacology Protein Binding TNF-Related Apoptosis-Inducing Ligand--metabolism