TY  - GEN
AU  - Youdim,Kuresh A
AU  - Lyons,Richard
AU  - Payne,Leon
AU  - Jones,Barry C
AU  - Saunders,Kenneth
TI  - An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point
SN  - 0731-7085
PY  - 2008///1126
KW  - Aryl Hydrocarbon Hydroxylases
KW  - analysis
KW  - Biological Assay
KW  - Chromatography, Liquid
KW  - methods
KW  - Cytochrome P-450 CYP1A2
KW  - Cytochrome P-450 CYP2B6
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP2D6
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - Dextromethorphan
KW  - metabolism
KW  - Diclofenac
KW  - Drug Interactions
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Inhibitory Concentration 50
KW  - Kinetics
KW  - Microsomes, Liver
KW  - chemistry
KW  - Midazolam
KW  - Miniaturization
KW  - Oxidoreductases, N-Demethylating
KW  - Reference Standards
KW  - Reproducibility of Results
KW  - Sensitivity and Specificity
KW  - Substrate Specificity
KW  - drug effects
KW  - Tacrine
KW  - Tandem Mass Spectrometry
KW  - Time Factors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.jpba.2008.05.011
ER  -