TY - GEN AU - Pockros,Paul J AU - Nelson,David AU - Godofsky,Eliot AU - Rodriguez-Torres,Maribel AU - Everson,Gregory T AU - Fried,Michael W AU - Ghalib,Reem AU - Harrison,Stephen AU - Nyberg,Lisa AU - Shiffman,Mitchell L AU - Najera,Isabel AU - Chan,Anna AU - Hill,George TI - R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin SN - 1527-3350 PY - 2008///0905 KW - Adult KW - Aged KW - Aged, 80 and over KW - Alanine Transaminase KW - blood KW - Antiviral Agents KW - administration & dosage KW - Cytidine KW - analogs & derivatives KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Drug Resistance, Viral KW - Drug Synergism KW - Drug Therapy, Combination KW - Female KW - Hepacivirus KW - enzymology KW - Humans KW - Interferon alpha-2 KW - Interferon-alpha KW - adverse effects KW - Male KW - Middle Aged KW - Neutropenia KW - chemically induced KW - Nucleosides KW - Polyethylene Glycols KW - Prodrugs KW - RNA, Viral KW - antagonists & inhibitors KW - Recombinant Proteins KW - Ribavirin KW - Treatment Outcome KW - Viral Load N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial UR - https://doi.org/10.1002/hep.22357 ER -