TY - GEN AU - Kessenbrock,Kai AU - Fröhlich,Leopold AU - Sixt,Michael AU - Lämmermann,Tim AU - Pfister,Heiko AU - Bateman,Andrew AU - Belaaouaj,Azzaq AU - Ring,Johannes AU - Ollert,Markus AU - Fässler,Reinhard AU - Jenne,Dieter E TI - Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin SN - 0021-9738 PY - 2008///0925 KW - Animals KW - Antigen-Antibody Complex KW - pharmacology KW - Arthus Reaction KW - metabolism KW - Cell Movement KW - drug effects KW - Chemotaxis, Leukocyte KW - Granulins KW - Inflammation KW - drug therapy KW - Intercellular Signaling Peptides and Proteins KW - Leukocyte Elastase KW - genetics KW - Mice KW - Mice, Inbred Strains KW - Mice, Knockout KW - Models, Biological KW - Myeloblastin KW - Neutrophil Activation KW - Neutrophils KW - cytology KW - Ovalbumin KW - immunology KW - Progranulins KW - Respiratory Burst KW - Tetradecanoylphorbol Acetate N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI34694 ER -