TY - GEN AU - LaVallee,Theresa M AU - Burke,Patricia A AU - Swartz,Glenn M AU - Hamel,Ernest AU - Agoston,Gregory E AU - Shah,Jamshed AU - Suwandi,Lita AU - Hanson,Art D AU - Fogler,William E AU - Sidor,Carolyn F AU - Treston,Anthony M TI - Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198 SN - 1535-7163 PY - 2008///0822 KW - 2-Methoxyestradiol KW - Administration, Oral KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Apoptosis KW - drug effects KW - Binding, Competitive KW - Cell Line, Tumor KW - Cell Proliferation KW - Colchicine KW - pharmacology KW - Drug Screening Assays, Antitumor KW - Estradiol KW - analogs & derivatives KW - Estrenes KW - G2 Phase KW - Hepatocytes KW - Humans KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - metabolism KW - Inhibitory Concentration 50 KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Microtubules KW - Mitosis KW - Rats KW - Survival Analysis KW - Tubulin KW - Tubulin Modulators N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/1535-7163.MCT-08-0107 ER -