Kreft, Anthony

Discovery of a novel series of Notch-sparing gamma-secretase inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jul 2008 - 4232-6 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2008.05.064 doi


Alzheimer Disease--drug therapy
Amyloid--chemistry
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Carbon--chemistry
Chemistry, Pharmaceutical--methods
Drug Design
Drug Evaluation, Preclinical
Enzyme Inhibitors--chemical synthesis
Humans
Models, Chemical
Receptors, Notch--antagonists & inhibitors
Structure-Activity Relationship