TY  - GEN
AU  - Kasper,Stefan
AU  - Breitenbuecher,Frank
AU  - Hoehn,Yvette
AU  - Heidel,Florian
AU  - Lipka,Daniel B
AU  - Markova,Boyka
AU  - Huber,Christoph
AU  - Kindler,Thomas
AU  - Fischer,Thomas
TI  - The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia
SN  - 0145-2126
PY  - 2008///1003
KW  - Acrylonitrile
KW  - analogs & derivatives
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Blotting, Western
KW  - Bone Marrow
KW  - Cell Differentiation
KW  - Cell Proliferation
KW  - Colony-Forming Units Assay
KW  - Cytarabine
KW  - administration & dosage
KW  - Daunorubicin
KW  - Drug Therapy, Combination
KW  - Female
KW  - Fluorescent Antibody Technique
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - drug therapy
KW  - Male
KW  - Mice
KW  - Middle Aged
KW  - Point Mutation
KW  - Signal Transduction
KW  - Styrenes
KW  - Tissue Distribution
KW  - Tumor Cells, Cultured
KW  - fms-Like Tyrosine Kinase 3
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.leukres.2008.05.003
ER  -