Kasper, Stefan <br/><br/>
The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia.  [electronic resource] 

 -  Leukemia research  Nov 2008 
 - 1698-708 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0145-2126 
<br/><br/><label>Standard No.: </label>10.1016/j.leukres.2008.05.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acrylonitrile--analogs & derivatives<br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Bone Marrow--drug effects<br/>Cell Differentiation--drug effects<br/>Cell Proliferation--drug effects<br/>Colony-Forming Units Assay<br/>Cytarabine--administration & dosage<br/>Daunorubicin--administration & dosage<br/>Drug Therapy, Combination<br/>Female<br/>Fluorescent Antibody Technique<br/>Humans<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Male<br/>Mice<br/>Middle Aged<br/>Point Mutation<br/>Signal Transduction--drug effects<br/>Styrenes--pharmacology<br/>Tissue Distribution<br/>Tumor Cells, Cultured<br/>fms-Like Tyrosine Kinase 3--antagonists & inhibitors